Monte Carlo in radiotherapy: experience in a distributed computational environment
نویسندگان
چکیده
New technologies in cancer radiotherapy need a more accurate computation of the dose delivered in the radiotherapeutical treatment plan, and it is important to integrate sophisticated mathematical models and advanced computing knowledge into the treatment planning (TP) process. We present some results about using Monte Carlo (MC) codes in dose calculation for treatment planning. A distributed computing resource located in the Technologies and Health Department of the Italian National Institute of Health (ISS) along with other computer facilities (CASPUR Inter-University Consortium for the Application of Super-Computing for Universities and Research) has been used to perform a fully complete MC simulation to compute dose distribution on phantoms irradiated with a radiotherapy accelerator. Using BEAMnrc and GEANT4 MC based codes we calculated dose distributions on a plain water phantom and air/water phantom. Experimental and calculated dose values below ±2% (for depth between 5 mm and 130 mm) were in agreement both in PDD (Percentage Depth Dose) and transversal sections of the phantom. We consider these results a first step towards a system suitable for medical physics departments to simulate a complete treatment plan using remote computing facilities for MC simulations . E-mail: [email protected]
منابع مشابه
Investigation and Comparison of Metal Nanoparticles on Dose Enhancement Effect in Radiotherapy Using Monte Carlo Simulation Method
Introduction: The main goal of radiation therapy is destroying the tumor so that the surrounded healthy tissues have received the least amount of radiation at the same time. In recent years, the use of nanoparticles has received much attention due to the increasing effects they can have on the deposited dose into the cancer cells. The aim of this study was to investigate the effects of nanopart...
متن کاملThe dosimetry assessment of Varian Linear Accelerators of 6, 15 and 20 MV by Monte Carlo Method
Introduction: Monte Carlo method is often applied in radiation therapy as utilized in all the branches of science. An important requirement for successful radiotherapy is carefully examine the dose distribution specifications and decrease the difference between these features with experience to an acceptable level. In this study, the characteristics of 6, 15 and 20 MeV incident x-rays are prov...
متن کاملEvaluation of Lung Dose in Esophageal Cancer Radiotherapy Using Monte Carlo Simulation
Background and purpose: Radiation therapy make an important contribution in the control and treatment of cancers. Lungs are the main organs at risk in esophageal cancer radiotherapy. Difference between the dose distribution due to the treatment planning system (TPS) and the patient's body dose is dependent on the calculation of the treatment planning system algorithm, which is more pronounced i...
متن کاملAn Efficiency Studying of an Ion Chamber Simulation Using Vriance Reduction Techniques with EGSnrc
Background: Radiotherapy is an important technique of cancer treatment using ionizing radiation. The determination of total dose in reference conditions is an important contribution to uncertainty that could achieve 2%. The source of this uncertainty comes from cavity theory that relates the in-air cavity dose and the dose to water. These correction factors are determined from Monte Carlo calcu...
متن کاملInvestigation of the dose enhancement effect due to gold nanoparticles at 18 MV radiotherapy using MAGIC-f and Monte Carlo methods Thoraco-Lumbar spinal cord fMRI in 3T Magnetic field
Introduction: Normoxic MAGIC-f polymer gels are established dosimeters used for three dimensional dos uantifications in radiotherapy. The high atomic number nanoparticles such as gold are nov adiosensitizers used to enhance doses delivered to tumors. The aim of this study was t vestigate the effect of gold nanoparticles (GNPs) in enhancing percentage depth doses (PDD ithin the...
متن کامل